Acetylcholinesterase Inhibition Improves Tachycardia in Postural Tachycardia Syndrome

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Acetylcholinesterase inhibition improves tachycardia in postural tachycardia syndrome.

BACKGROUND Postural tachycardia syndrome (POTS) induces disabling chronic orthostatic intolerance notable for an excessive increase in heart rate that occurs on standing. Many current therapeutic strategies focus on sympatholysis, but the alternative strategy of enhancing cardiovagal tone has not been studied. The objective of this study was to test the hypothesis that acetylcholinesterase inhi...

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Ascorbate improves circulation in postural tachycardia syndrome.

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Postural tachycardia syndrome (POTS).

INTRODUCTION POTS is defined as the development of orthostatic symptoms associated with a heart rate (HR) increment >or=30, usually to >or=120 bpm without orthostatic hypotension. Symptoms of orthostatic intolerance are those due to brain hypoperfusion and those due to sympathetic overaction. METHODS We provide a review of POTS based primarily on work from the Mayo Clinic. RESULTS Females p...

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Postural tachycardia syndrome (POTS).

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Postural tachycardia syndrome.

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ژورنال

عنوان ژورنال: Circulation

سال: 2005

ISSN: 0009-7322,1524-4539

DOI: 10.1161/circulationaha.104.497594